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IONIS PHARMACEUTICALS INC

IONS · XNAS

CIK 874015fmd_0V7467XKTX0RQQWQMBD2SP614EManufacturing · Pharmaceutical PreparationsTemplate: Standard

Coverage: Jan 01, 2008 to Sep 30, 2026, 71 periods

Latest annual · FY2025

Millions
Total revenues
944
Gross profit
928
Operating income
(382)
Net income
(381)
Free cash flow
(320)

Latest quarter · Q3 FY2026

Millions
Total revenues
243
Gross profit
239
Operating income
(131)
Net income
(110)
Free cash flow
(192)

Daily close · IONSIEX trades only

Nov 13, 2025 to Nov 11, 2026 · 250 sessions

28.32 USD

20406080100Nov 13, 2025May 14, 2026Nov 11, 2026Vol

Built from trades executed at IEX only, one exchange with a small share of US volume. This is not the consolidated tape. The close is the last IEX trade of the session, not the official closing price. Earlier sessions are divided by the later split ratios the API confirmed against IEX prices; dividends are not adjusted. Switch to As traded for the prices as they printed. End of day, not real time: a session is published the day after it trades.

Data provided for free by IEX. By accessing or using IEX Historical Data, you agree to the IEX Historical Data Terms of Use. iex.io/legal/hist-data-terms

Open Financials

Key stats

Open Analysis

Compound annual growth

Revenue, 3 yearsFY2022 to FY2025
+17.1%
Revenue, 5 yearsFY2020 to FY2025
+5.3%
Net income, 5 yearsFY2020 to FY2025
n/m

IONIS PHARMACEUTICALS INC (IONS) financials: quick answers

Annual figures as filed with the SEC. Each number links to the filing it came from and to its proof.

MetricFY2025FY2024ChangeSource
Revenue$943.7 million$705.1 million+33.8%10-K 2026-02-26 · proof
Gross profit$927.8 million$693.9 million+33.7%10-K 2026-02-26 · proof
Operating income-$381.7 million-$475.1 million10-K 2026-02-26 · proof
Net income-$381.4 million-$453.9 million10-K 2026-02-26 · proof
Cash from operating activities-$268.6 million-$500.9 million10-K 2026-02-26 · proof
Free cash flow-$320 million-$546.2 million10-K 2026-02-26 · proof
Total assets$3.5 billion$3 billion+17.3%10-K 2026-02-26 · proof
Total liabilities$3 billion$2.4 billion+25.6%10-K 2026-02-26 · proof
Cash and cash equivalents$372.3 million$242.1 million+53.8%10-K 2026-02-26 · proof
Total debt$1.8 billion$1.2 billion+46.4%10-K 2026-02-26 · proof
What was IONIS PHARMACEUTICALS INC (IONS)'s revenue in fiscal 2025?
IONIS PHARMACEUTICALS INC (IONS) reported revenue of $943.7 million for fiscal 2025 (the year ended Dec 31, 2025), against $705.1 million the year before (+33.8%). Source: the 10-K filed with the SEC on Feb 26, 2026. SEC
What was IONIS PHARMACEUTICALS INC (IONS)'s gross profit in fiscal 2025?
IONIS PHARMACEUTICALS INC (IONS) reported gross profit of $927.8 million for fiscal 2025 (the year ended Dec 31, 2025), against $693.9 million the year before (+33.7%). Source: the 10-K filed with the SEC on Feb 26, 2026. SEC
What was IONIS PHARMACEUTICALS INC (IONS)'s operating income in fiscal 2025?
IONIS PHARMACEUTICALS INC (IONS) reported operating income of -$381.7 million for fiscal 2025 (the year ended Dec 31, 2025), against -$475.1 million the year before. Source: the 10-K filed with the SEC on Feb 26, 2026. SEC
What was IONIS PHARMACEUTICALS INC (IONS)'s net income in fiscal 2025?
IONIS PHARMACEUTICALS INC (IONS) reported net income of -$381.4 million for fiscal 2025 (the year ended Dec 31, 2025), against -$453.9 million the year before. Source: the 10-K filed with the SEC on Feb 26, 2026. SEC
What was IONIS PHARMACEUTICALS INC (IONS)'s cash from operating activities in fiscal 2025?
IONIS PHARMACEUTICALS INC (IONS) reported cash from operating activities of -$268.6 million for fiscal 2025 (the year ended Dec 31, 2025), against -$500.9 million the year before. Source: the 10-K filed with the SEC on Feb 26, 2026. SEC
What was IONIS PHARMACEUTICALS INC (IONS)'s free cash flow in fiscal 2025?
IONIS PHARMACEUTICALS INC (IONS) reported free cash flow of -$320 million for fiscal 2025 (the year ended Dec 31, 2025), against -$546.2 million the year before. Source: the 10-K filed with the SEC on Feb 26, 2026. SEC
What are IONIS PHARMACEUTICALS INC (IONS)'s total assets?
As of Dec 31, 2025, IONIS PHARMACEUTICALS INC (IONS) reported total assets of $3.5 billion, against $3 billion a year earlier (+17.3%). Source: the 10-K filed with the SEC on Feb 26, 2026. SEC
What are IONIS PHARMACEUTICALS INC (IONS)'s total liabilities?
As of Dec 31, 2025, IONIS PHARMACEUTICALS INC (IONS) reported total liabilities of $3 billion, against $2.4 billion a year earlier (+25.6%). Source: the 10-K filed with the SEC on Feb 26, 2026. SEC
What are IONIS PHARMACEUTICALS INC (IONS)'s cash and cash equivalents?
As of Dec 31, 2025, IONIS PHARMACEUTICALS INC (IONS) reported cash and cash equivalents of $372.3 million, against $242.1 million a year earlier (+53.8%). Source: the 10-K filed with the SEC on Feb 26, 2026. SEC
What is IONIS PHARMACEUTICALS INC (IONS)'s total debt?
As of Dec 31, 2025, IONIS PHARMACEUTICALS INC (IONS) reported total debt of $1.8 billion, against $1.2 billion a year earlier (+46.4%). Source: the 10-K filed with the SEC on Feb 26, 2026. SEC

Read from the FinancialMD API on Nov 13, 2026. Values change only when a new filing is made; see the Financials tab for every period and as-of replay.

The same numbers for an agent, with proof on every value:

curl "https://api.financial.md/v1/company/financials/income_statement/standardized?company=ticker:IONS&period_type=annual&limit=5"

Information only, not investment advice.